How Businesses Can Access R&D Infrastructure

Accessing Science Without Building It: A Practical R&D Model for Bio-Based Innovation

BIORESOURCES Editorial Team · 9 min read

A nutraceutical startup or a SME with a promising plant extract doesn’t need its own chromatography lab, cell-culture facility, microbiology lab and formulation team to find out whether the extract actually works. It needs access to those capabilities for as long as the question takes to answer, and a clear plan for what comes next. That’s the practical alternative to building an R&D department from scratch – and it’s the model BIORESOURCES Centre of Competence in Sofia was built to offer businesses developing bio-based products from medicinal and aromatic plants.

Key Insights

  • Building multidisciplinary R&D capability in-house – plant science, extraction, analytical chemistry, biological testing, formulation – is slow, expensive, and, for most companies, never fully used once it exists.
  • BIORESOURCES gives businesses access to that capability on a project basis, without the capital cost or hiring risk of building it internally.
  • A project can start anywhere: a raw plant material, an extract, a research result, an early formulation, or simply a product idea.
  • Collaboration can be scoped as a single laboratory service or as a fully integrated, multi-stage project – the right scope depends on what evidence you already have and what’s missing.
  • The goal at every stage is to reduce technical uncertainty before you commit to scale-up, regulatory work, or a market launch.
  • Every engagement starts with a conversation about your specific project, not a fixed quote for a fixed package.

The real cost of building R&D capability in-house

Developing a bio-based product – a nutraceutical ingredient, a cosmetic active, a functional food component – touches several scientific disciplines at once: plant science and agronomy, extraction and analytical chemistry, microbiology or cell biology, and formulation science. Very few companies have all of that in-house, and fewer still need it permanently.

Building it from scratch means hiring specialists whose disciplines rarely overlap day to day, buying instrumentation that depreciates whether or not it’s running, and carrying that cost through the months when a project stalls, changes direction, or turns out to need a different test than the one your equipment was bought for.

For a startup, that level of investment is usually impossible before the first funding round – and the first funding round usually depends on having evidence the startup doesn’t yet have. For an established company testing a new ingredient category, it’s a slow, capital-intensive way to explore something that might not pan out.

Access, not ownership

BIORESOURCES exists to make the alternative straightforward: instead of building the laboratory, you access it – and the scientists who run it – for exactly the work your project needs.

That means specialist laboratories and scientific teams across plant biotechnology, molecular genetics, phytochemistry, analytical chemistry, cell-based biological testing, polymer science, and formulation, brought together from the Bulgarian Academy of Sciences, the Agricultural Academy, and Sofia University “St. Kliment Ohridski” – without you having to negotiate separately with each institution or work out which lab does what.

You pay for the work your project needs, when it needs it, rather than for capacity you might use eventually.

Start wherever your project actually is

There’s no single entry point businesses are expected to arrive at. A project can start with:

  • a raw plant, agricultural by-product, or other bioresource that hasn’t been evaluated yet;
  • an extract, isolated compound, or synthesized substance that needs to be analysed or tested
  • a research result – internal or licensed – that needs independent validation;
  • an early formulation that needs to be stabilized, characterized, or improved;
  • or simply a product idea with no material or data behind it yet.

Whichever of these describes your project, it maps onto the same underlying pathway – from raw material through extraction, analysis, biological testing, and formulation to a laboratory prototype (see From Bioresource to Innovative Product for the full pathway). You don’t start over at stage one just because you arrived with an idea instead of a sample, and you don’t pay for stages you’ve already completed elsewhere.

The real first step is a question, not a test

It’s tempting to start a conversation with a lab by asking for a specific test – “can you run an analysis on this extract” – but the more useful starting point is usually one step earlier: what does this project actually need to know right now, and what evidence is missing to know it?

A test run without that framing can produce a technically correct result that doesn’t actually answer the business question behind it. Before any lab work begins, BIORESOURCES experts work through what’s already known, what’s assumed, and where the real uncertainty sits – plant identity and consistency, compound presence, biological activity, formulation stability, or something else entirely. That scoping conversation is what turns a vague ask into a development plan with a defined, useful output.

One test or a full project - the choice is yours

Not every business needs, or can justify, a multi-stage engagement. BIORESOURCES supports both ends of that spectrum:

  1. A single service – one analytical run, one biological assay, one formulation trial – for a business that needs a specific answer before deciding whether to go further.

     

  2. An integrated, multi-stage project – spanning raw-material evaluation through formulation and prototyping – for a business ready to move a concept through the full development pathway under one coordinated plan.

Many projects start as the former and grow into the latter once the first result justifies the next step. Neither path requires committing to the whole pathway upfront.

Reducing risk before the expensive decisions

Scale-up, regulatory submission, and market launch are the stages where mistakes are hardest and most expensive to reverse – a formulation that fails stability testing after tooling has been ordered, or a claim that can’t be substantiated after marketing materials are printed.

The work BIORESOURCES supports is designed to surface those problems earlier, while they’re still cheap to fix confirming raw-material consistency before locking in a supplier, validating biological activity before making a claim, testing formulation stability before committing to packaging and production. None of this replaces the industrial manufacturing, quality, and regulatory processes a finished product ultimately needs – but it substantially narrows the uncertainty a business carries into those later, costlier stages.

From a single conversation to a structured development plan

Working with BIORESOURCES doesn’t start with a quote for a fixed package of services. It starts with a conversation about the project:

  1. Initial discussion – you describe the bioresource, result, formulation, or idea, and the problem you’re trying to solve.

  2. Needs assessment – BIORESOURCES experts review what evidence already exists and where the real gaps are.

  3. Development plan – the specific analyses, experiments, laboratories, timeline, and responsibilities are defined and agreed before any work starts.

  4. Scientific and laboratory work – the agreed activities are carried out.

  5. Interpretation and next steps – the results are translated into a recommendation: proceed, adjust the approach, or gather more evidence first.

You don’t need a finished research brief to start this process – describing where your project stands today is enough.

Who this is for

This model tends to fit four kinds of businesses particularly well:

  • Startups with a promising plant, extract, or idea who need evidence before – or instead of – building an internal R&D team.
  • SMEs looking to validate, improve, or extend an existing product line into a new category, such as a food producer moving into functional ingredients.
  • Established companies exploring a new bio-based ingredient or category without redirecting their existing R&D resources away from current priorities.
  • Any of the above facing a specific technical roadblock – an unstable formulation, an inconclusive test, an inconsistent raw material – that needs outside expertise to resolve.

Where nature meets science - and business meets both

The businesses that get the most out of this model aren’t the ones with the most resources. They’re the ones willing to start with a real conversation about where their project stands, rather than either building a lab they don’t need or guessing their way past a scientific question they can’t yet answer.

BIORESOURCES Centre of Competence is supported under Project BG16RFPR002-1.014-0001, “Sustainable Utilization of Bioresources from Medicinal and Aromatic Plants for Innovative Products” (BIORESOURCES BG), funded by the Programme “Research, Innovation and Digitalisation for Smart Transformation” and co-funded by the European Union.

Do you have a plant, extract, formulation, or product idea that needs scientific evidence behind it?

Contact BIORESOURCES to describe your project and find out what the most useful next step looks like.

Frequently Asked Questions

Do we need a fully developed R&D plan before contacting BIORESOURCES?

No. Most projects start with a description of the bioresource, result, formulation, or idea and the problem behind it. BIORESOURCES experts help shape the specific questions and plan from there.

Can we start with a single test before committing to a larger project?

Yes. Collaboration can be scoped as one laboratory service – an analysis, a biological assay, a formulation trial – or as an integrated, multi-stage project. Many businesses start with one and expand once the result justifies it.

How is a project scoped, and what does it cost?

Each project is scoped individually during the initial discussion and needs assessment, based on the specific analyses, laboratories, and timeline required. There’s no fixed package or price list, since the right scope depends entirely on the project.

Do we need in-house scientific expertise to work with BIORESOURCES?

No. Part of the value of working with the Centre is that it supplies the scientific expertise you don’t have to build internally. You bring the bioresource, result, or idea; BIORESOURCES experts help translate it into a workable development plan.

Who owns the intellectual property generated during a project?

IP arrangements are discussed and agreed as part of scoping a project, and BIORESOURCES can provide guidance on intellectual-property considerations as part of its expert support. Specific terms are set out per collaboration.

Can BIORESOURCES help us decide if an idea is worth pursuing before we invest further?

Yes – that’s often exactly where a first conversation is most useful. A focused piece of analytical or biological evidence can confirm whether an idea is worth taking further before a business commits to a bigger investment.

Does BIORESOURCES work with companies outside Bulgaria?

BIORESOURCES supports businesses and research organizations more broadly, not only those based in Bulgaria. The best way to confirm fit for a specific project is to reach out directly.

What happens after the scientific work is finished?

Results are translated into a recommendation for what comes next – further validation, formulation or prototyping work, scale-up planning, or preparation for regulatory or commercialization steps. BIORESOURCES doesn’t replace industrial manufacturing or regulatory approval, but it can help identify the appropriate next stage and, where relevant, a manufacturing or industry partner.

What if we're not sure which stage of the pathway our project is at?

That’s a normal starting point. Describing what you have – a plant, an extract, a result, a formulation, or just an idea – is enough for BIORESOURCES experts to assess the current stage and the most relevant next step.